Eleni Aklillu Selected Research

efavirenz (Sustiva)

1/2022	Prevalence and predictors of glucose metabolism disorders among People Living with HIV on combination antiretroviral therapy.
1/2021	Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients.
1/2020	Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations.
11/2018	Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype.
11/2018	Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin.
1/2017	Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs.
12/2016	Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients.
8/2016	Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: A prospective cohort study.
4/2016	CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population.
4/2015	The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatment.

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Eleni Aklillu Research Topics

Disease

20	Tuberculosis (Tuberculoses) 03/2022 - 03/2008
11	Coinfection 11/2022 - 03/2008
11	Malaria 12/2021 - 04/2015
7	Schistosomiasis (Bilharziasis) 01/2022 - 12/2019
7	Infections 12/2021 - 10/2012
6	Body Weight (Weight, Body) 12/2019 - 05/2010
4	Schistosomiasis mansoni 04/2021 - 12/2019
4	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2019
4	Chemical and Drug Induced Liver Injury 01/2017 - 01/2011
3	Filarial Elephantiasis (Lymphatic Filariasis) 05/2022 - 05/2020
3	COVID-19 03/2022 - 12/2021
3	Pregnancy Complications 12/2021 - 07/2019
2	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2021 - 06/2019
2	HIV Infections (HIV Infection) 01/2021 - 06/2013
2	Schizophrenia (Dementia Praecox) 01/2020 - 05/2010
2	Anemia 01/2020 - 01/2019
2	Vitamin D Deficiency 01/2019 - 08/2016
2	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2017 - 01/2016
2	Acquired Immunodeficiency Syndrome (AIDS) 01/2015 - 08/2011
2	Lung Neoplasms (Lung Cancer) 03/2013 - 06/2005
2	Hepatocellular Carcinoma (Hepatoma) 06/2009 - 09/2003
2	Neoplasms (Cancer) 06/2005 - 03/2002
1	Communicable Diseases (Infectious Diseases) 03/2022
1	Respiratory Tract Infections (Respiratory Tract Infection) 03/2022
1	Glucose Metabolism Disorders 01/2022
1	Drug-Related Side Effects and Adverse Reactions 01/2021
1	Neglected Diseases 05/2020
1	Overweight 03/2020
1	Fever (Fevers) 02/2020
1	Dyslipidemias (Dyslipidemia) 03/2019
1	Thrombocytopenia (Thrombopenia) 01/2019
1	Neutropenia 01/2019
1	Inflammation (Inflammations) 01/2017
1	Immune Reconstitution Inflammatory Syndrome 01/2015
1	Sleep Initiation and Maintenance Disorders (Insomnia) 06/2013
1	Hallucinations (Hallucination) 06/2013
1	Sleep Wake Disorders 06/2013

Drug/Important Bio-Agent (IBA)

15	efavirenz (Sustiva)FDA Link 01/2022 - 01/2011
11	Rifampin (Rifampicin)FDA LinkGeneric 11/2022 - 01/2011
9	Pharmaceutical PreparationsIBA 01/2022 - 03/2008
9	EnzymesIBA 01/2022 - 03/2002
7	Praziquantel (Biltricide)FDA Link 01/2022 - 12/2019
6	Cytochrome P-450 CYP3AIBA 01/2021 - 08/2011
6	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 02/2020 - 04/2015
5	Lumefantrine FDA Link 02/2020 - 04/2015
4	Albendazole (Albenza)FDA Link 05/2022 - 05/2020
4	pyrimethamine drug combination fanasil (Fansidar)FDA Link 12/2021 - 07/2019
4	Cytochrome P-450 CYP2B6 (CYP2B6)IBA 11/2018 - 06/2013
4	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 03/2013 - 09/2003
3	VaccinesIBA 03/2022 - 12/2021
3	artenimol (dihydroartemisinin)IBA 12/2021 - 01/2020
3	piperaquineIBA 12/2021 - 01/2020
2	Ivermectin (Mectizan)FDA Link 05/2022 - 05/2020
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 01/2019
2	Olanzapine (Zyprexa)FDA Link 01/2020 - 05/2010
2	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 09/2019 - 11/2007
2	Tamoxifen FDA LinkGeneric 09/2019 - 01/2019
2	Antimalarials (Antimalarial Agents)IBA 04/2019 - 04/2015
2	CholesterolIBA 03/2019 - 08/2016
2	Vitamin D FDA LinkGeneric 01/2019 - 08/2016
2	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2017 - 03/2014
2	Antitubercular AgentsIBA 09/2016 - 01/2012
2	Biomarkers (Surrogate Marker)IBA 03/2014 - 01/2011
2	Alanine Transaminase (SGPT)IBA 03/2014 - 08/2011
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 08/2011 - 06/2005
2	Antipsychotic Agents (Antipsychotics)IBA 11/2007 - 02/2006
1	NucleotidesIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	rifapentine (Priftin)FDA Link 01/2022
1	RifamycinsIBA 01/2022
1	Atazanavir Sulfate (Reyataz)FDA Link 01/2022
1	Ritonavir (Norvir)FDA Link 01/2022
1	Diethylcarbamazine (Hetrazan)FDA Link 03/2021
1	Moxifloxacin (Avelox)FDA Link 01/2021
1	Levofloxacin (Levaquin)FDA Link 01/2021
1	Warfarin (Coumadin)FDA LinkGeneric 03/2020
1	Coffee FDA Link 01/2020
1	Hemoglobins (Hemoglobin)IBA 01/2020
1	4-hydroxy-N-desmethyltamoxifenIBA 09/2019
1	Triglycerides (Triacylglycerol)IBA 03/2019
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2019
1	HLA-B57 antigenIBA 01/2017
1	Floxacillin (Flucloxacillin)IBA 01/2017
1	8-hydroxyefavirenzIBA 12/2016
1	hydroxide ionIBA 08/2016
1	Cytochrome P-450 CYP2C9IBA 06/2015
1	Nevirapine (Viramune)FDA Link 04/2015
1	RNA (Ribonucleic Acid)IBA 01/2015
1	ImmunosorbentsIBA 03/2014
1	Keratin-18 (Keratin 18)IBA 03/2014
1	Complement System Proteins (Complement)IBA 03/2014
1	Caffeine (No Doz)FDA LinkGeneric 03/2013

Therapy/Procedure

22	Therapeutics 11/2022 - 02/2006
11	Drug Therapy (Chemotherapy) 05/2022 - 02/2006
9	Highly Active Antiretroviral Therapy (HAART) 01/2022 - 01/2012
3	Mass Drug Administration 05/2022 - 01/2020
2	Prenatal Care (Care, Prenatal) 03/2020 - 01/2020
1	Precision Medicine 03/2022
1	Aftercare (After-Treatment) 01/2017
1	Art Therapy 04/2015